IWA 15 : Track and verification of pipettor performance using colorimetry and gravimetry measurement

  We describe hereby a method verification done on a pipettor equiped with a 96 wells head and Tartrazine dye distribution (the process could also be done with a 384 wells head).

* Gravimetric tests : Enable accuracy verification

Dispense of various volume of Tartrazine Dye solution with ON-LINE weighting of the whole plate before and after dispense with an integrated Moduloplate SCALE. Each volume is made in triplicate.

 
* Colorimetric tests : Enable precision measurement

Just after the weighting,Tartrazine is mixed with aspiration/dispense and then read on an absorbance reader.

 

The complete process of 12 measurements is done within less than 30 minuts on a CyBio-FeliX pipettor including absorbance reading of 3 microplates in 384 well Format

Then results are exported in a spreadsheet software or ideally in the DISCNGINE 'Qualification' software to manage the results.

This kind of software make the treatment and overview of the results easy and enable standardisation of processes and calculation over different platforms and laboratories thanks to the Cloud access mode.

Media

Moduloplate™ Scale can be placed into any platform alongside the sample while pipetting or dispensing protocols. This way of use provides measurement on the fly of dispensed liquid within microplates.
Moduloplate Scale on Perkin Elmer® Multiprobe platform Moduloplate Scale on Zinsser analytic® pipeting platform
Perkin Elmer® Multiprobe platform
Zinsser analytic® pipeting platform

 

Moduloplate™ Scale is easy to fits with CyBio products ( www.cybio.fr) :

Moduloplate Scale on CyBi-Selma pipetor

Moduloplate Scale on CyBi-Well flex vario

CyBio®  CyBi-Selma
pipetor
CyBio® CyBi-Well flex vario
pipetor
 
 Moduloplate™ Scale design is compatible with grippers; stackers or robotic arms. With a such compatibility, the device can be removed without human intervention.
                                 

Moduloplate Scale with robotic_arm_200

Moduloplate Scale with gripper

Rotating arm/gripper
Robotic arm

 

At Fixed Volumes
On the Fly Calibration of liquid dispensor (example CyBi-Drop) with Moduloplate Scale On the Fly Calibration of liquid dispensor (example CyBi-Drop) with Moduloplate Scale
  Moduloplate™ allows to follow real time dispensing  into microplate at fixed volumes with liquid dispensor like the CyBi-Drop.
 
  With Moduloplate™, it's not necessary to weigh your microplate after samples distribution. The Moduloplate™ Scale shows you the progression of your protocl and enables you to adjust the device's calibration with a great precision.
 

At Variable Volumes
On the Fly Calibration of liquid dispensor (example CyBi-Drop) with Moduloplate Scale On the Fly Calibration of liquid dispensor (example CyBi-Drop) with Moduloplate Scale
  With the expected weight, you can directly compare the measured weight  and calibrate your CyBi-Drop for the best precision.

Moduloplate™ Scale is a great solution to achieve  easy and quick calibration of your liquids dipensors.

 

 

Moduloplate™ Scale allows you to follow in real time remaining volume into reference microtubes, microplates as well as into reservoirs.

Evolution of microplate Weight after every pipeting with Moduloplate Scale

With the Moduloplate™ Scale, you could do gravity calibration of your liquid handler or dispensor.
You could also record results with your own protocol and follow the liquid handling behavior and quality.

Calibration of pipeting hads by gravity test with Moduloplate Scale

 

 

Liquid handling calibration via gravity methods with Moduloplate Scale

 

You can calibrate or check liquid handling devices or dispensors in a few minutes, before starting your assay for optimal results.

Gravity testing is the most recognized and the easiest calibration test for Liquid handling.

With the Moduloplate™ Scale, you could do directly the calibration in a few minutes on your robotic platform bench with your own methods or protocols.

Moduloplate calibration of pipetting heads via gravity methods

In addition for a best performance, you could adapt parameters and tips according to your new written protocols.

 

 

Those standard accessories are provided with Moduloplate™ Scale for the best use of your device.

 

Moduloplate Scale storage box Moduloplate Panel Software Moduloplate Universal power adapter
Storage Box Software Universal Power Supply
Moduloplate Recharge Pod Moduloplate Bluetooth adapter Moduloplate reset/start/stop tools
Recharge Pod Bluetooth Adapter Reset/Start/Stop Tools
Moduloplate 100 grams calibration weight Moduloplate command codes Moduloplate Documentation
Calibration Weight Command Codes Documentation

 

 

 




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Moduloplate™ Panel Software


(1) Simultaneously connection of up to 8 modules

(2) Switch measuring modes

(3) Real time measurement

(4) Graphical display of recorded values

(5) Bluetooth connection indicator

(6) Switch Noise filter (High/Low)

(7) Record of measuring datas



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(6)


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SBS-Plate format that simply fits your robotic platform:

 

Moduloplate_scale_Dimension

Moduloplate™ Scale is specifically designed in standard SBS-Plate format in order to be managed by your robotic platform as any other microplates.

Moduloplate™ requires a small footprint on your platform and avoids use of laboratory classic balance oversized.

Its dedicated design fits most of usual microplates that will simple stand on top of the device.

Moduloplate™ is stackable and robotic arms are ready for maximum of mobility and flexibility.

 

Moreover, its size allows it to take over any microplate format

Moduloplate Scale with microplates 96 Wells

Moduloplate Scale with microplates 384 Wells
  
Moduloplate Scale with microtubes
                   
Microplates 96 Wells           Microplates 384 Wells         Microtubes   

   

 

 

                                                                                                                                        

Moduloplate™ Scale Overview Moduloplate™ Scale Overview Moduloplate™ Scale Overview Moduloplate™ Scale Overview Moduloplate™ Scale Overview

Characteristics

 

 

 

Moduloplate™ Scale Overview Moduloplate™ Scale Overview Moduloplate™ Scale Overview Moduloplate™ Scale Overview Moduloplate™ Scale Overview

Applications